One flat price. Medication, labs & unlimited clinician visits included. Prescription required; not all patients qualify.
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Menopause (HRT)

Estradiol and progesterone, or a hormone-free option

In plain words

During perimenopause and menopause, your body makes less estrogen. That drop causes hot flashes, night sweats, poor sleep and mood changes. HRT replaces some of that estrogen to ease these symptoms.

How it works

Your clinician picks the form and dose that fit you. If you still have a uterus, progesterone is added to protect its lining.

What’s inside, ingredient by ingredient

Estradiol

The same form of estrogen your body makes. Eases hot flashes, night sweats and vaginal dryness.

Progesterone

Protects the lining of the uterus when you take estrogen, and may help with sleep.

Paroxetine or desvenlafaxine

Hormone-free medicines that act on brain chemicals that control body temperature. Low-dose paroxetine is FDA-approved for menopause hot flashes.

How you take it

  • Estradiol cream: rub on the skin once a day
  • Estradiol patch: stick on your lower belly or hip, change twice a week
  • Estradiol tablet: once a day
  • Progesterone: one capsule by mouth, usually at bedtime
  • Hormone-free option: one tablet a day

Who it may be for

Women in perimenopause or menopause.

A licensed clinician decides if it’s right for you. Not everyone qualifies.

Plans & prices

Estradiol cream + progesterone
3 months (12 weeks)$237about $79 per 4 weeks
Estradiol patch + progesterone
3 months (12 weeks)$237about $79 per 4 weeks
Estradiol tablet + progesterone
3 months (12 weeks)$237about $79 per 4 weeks
Paroxetine or desvenlafaxine
3 months (12 weeks)$237about $79 per 4 weeks
From $79/4 weeks
Medication, visits and shipping included
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Important safety information

Compounded medications are prepared by licensed U.S. partner pharmacies, not by RYNA Health. They are not FDA-approved, which means the FDA does not review their safety, effectiveness or quality, and they are not the same as brand-name or generic drugs. Prescriptions are issued only after an evaluation by a licensed clinician, when appropriate. Individual results vary.

RYNA — Peptide Optimization

Clinician-prescribed, medically-supervised programs for weight, recovery, and longevity. Prescription products require a valid prescription and are dispensed only when clinically appropriate.

RYNA Health donates 20% of its profits to local nonprofits: Lost But Not Forgotten, Placer County Breast Cancer Foundation, Gi-Gi’s House, Keaton’s Child Cancer Alliance and 100+ Women Who Care.

Clinical support: message your care team in your patient account care@rynahealth.com Partner pharmacies · Serving all 50 states
Cancellation and Refund Policy

You may cancel your program at any time at no charge by emailing care@rynahealth.com or messaging us in your patient account. To avoid being billed for the next period, requests must be received at least 48 hours before your next scheduled billing date. If a licensed clinician determines that treatment is not clinically appropriate for you and no medication is prescribed, you will receive a full refund automatically. For patient-safety and regulatory reasons, prescription medication cannot be returned, resold, or refunded once dispensed and shipped, even if unopened. On multi-month plans, you may request a refund for any full, unshipped months remaining in your term; shipped or in-progress months are not refundable. If a shipment arrives damaged or does not arrive, contact us within 7 days for a replacement or refund. Approved refunds are returned to your original payment method within 5–10 business days. Full details: www.rynahealth.com — Cancellation and Refund Policy. Questions: care@rynahealth.com.

This site is not for medical emergencies. If you think you are having an emergency, call 911 or go to the nearest emergency room. This site is intended for adults 18 and over in the United States, and nothing here is medical advice or a substitute for care from your own clinician.

RYNA is a management services organization and is not a medical practice or pharmacy. Clinical services are provided by independent, licensed clinicians within an affiliated professional entity; medications are dispensed by independent, licensed pharmacies. RYNA does not practice medicine, provide medical advice, or dispense medication. Prescriptions are issued only after a professional medical evaluation and only when clinically appropriate, and not all patients qualify for every program or medication. Certain medications are compounded and are not reviewed or approved by the U.S. Food and Drug Administration for safety, efficacy, or manufacturing quality; availability and formulation may change at any time without notice. Prices shown are the total out-of-pocket amount paid through RYNA and may change with FDA and state regulations. Statements and reviews on this site reflect individual experience only and are not a guarantee of results; individual outcomes vary. Your Protected Health Information is handled in accordance with the applicable Notice of Privacy Practices and is not used for advertising or marketing analytics.

Clinical services are available through licensed clinicians in the states where our affiliated professional entity is authorized to operate. Not every program or medication is available in every state, and availability is subject to change without notice. Eligibility is confirmed during your medical evaluation.

© 2026 RYNA Health, LLC. All rights reserved.

Ryna Health

NEW: personalized HRT for menopause relief

Rediscover your vitality & balance

Estradiol & progesterone, personalized for you — cream, patch or tablet
$237 per 12-week supply (about $79 per 4 weeks)
Non-hormonal options, like paroxetine, also available
• Full refund if you’re not eligible• Cancel in one tap• Private & discreet

Prescription only, after an evaluation by a licensed clinician. HRT has risks, including blood clots and stroke, and isn’t right for everyone. Individual results vary.
Four men of different ages laughing together on a mountain terrace, under the words TRT, testosterone replacement therapy
Coming soon to RYNA Health

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